Tesamorelin, a synthetic peptide molecule contains 44 amino acids, similar to hGRF derivative. The chemical contains trans-3-Hexenoic acid group, and being commercialized as Egrifta. Initially, Tesamorelin was developed by a Canadian firm called Theratechnologies, Inc. Facilitates release of growth hormone via the pituitary gland and cause catabolism of excessive adipose abdominal fat. Clinical studies reported that Tesamorelin reduce lipodystrophy in HIV-infected patients. As a hypothalamic peptide, Tesamorelin promotes biosynthesis and release of growth hormone. Recent studies are investigating the effects on the pituitary somatotrophic cells, and additional studies are to be conducted in the core area.
Tesamorelin is a peptide in the category of GHRH peptides the hormone has shown immense results in reducing belly fat, enhancing fat and lipid distribution in the body and metabolism. The hormone stimulates the pituitary gland to secrete GH, which has an indirect approach in maintaining stable levels of GH in the system. Moreover, Tesamorelin promotes fat burning and lean body. Studies reveal that Tesamorelin does affect the levels of transaminases such as aspartate amino transferase and alanine amino transferase. As the level of the hormone increases so does the level o lipids. The C-reactive protein is not affected by serum increase of Tesamorelin however, the hormone increases adiponectin levels. Tesamorelin is known to increase the levels of growth hormone, which plays a crucial role in cell division, cell development, and maturity. An elated level of insulin like growth factor 1 is as a result of increase in Tesamorelin levels, which in turn increases glycosylated hemoglobin. The hypothalamic axis can be affected when the levels of the polypeptide is high.
Tesamorelin Chemical Profile
Molecular weight: 5135.9
Peptide purity: > 99.0%
Chain: N-(trans-3-hexenoyl)-[Tyr1]hGRF(1–44)NH2 acetate (CH3CH2CH=CHCH2CO-Tyr 1-Ala-Asp-Ala-Ile-Phe-ThrAsn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu
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|Packing Strength||1 x vial|