What is Genotropin
Genotropin is a form of HGH that is identical to the naturally occurring growth hormone produced in the human body. Genotropin is approved by the FDA for use in children with growth hormone deficiency, those born with small gestational age (SGA), idiopathic short stature (ISS), Prader-Willi syndrome (PWS), and for girls with Turner syndrome (TS). It also approved for use in adults suffering from growth hormone deficiency. Genotropin is a product of Pfizer Pharmaceuticals. Genotropin is very popular with a long record of safe use by patients. Genotropin is a form of bio-identical human growth hormone, meaning it shares the exact same biological composition as naturally made human growth hormone, it is simply made in a laboratory environment using recombinant-DNA technology. Because it is identical to the growth hormone produced by the human body there are very few side effects associated with it’s use. Bio-Identical HGH is actually far safer than naturally harvested human growht hormone, because there is effectively zero risk of contamination. It was also proven effective in clinical trials:
GENOTROPIN (somatropin [rdna origin]) lyophilized powder was compared with placebo in six randomized clinical trials involving a total of 172 adult GHD patients. These trials included a 6-month double-blind treatment period, during which 85 patients received GENOTROPIN (somatropin [rdna origin]) and 87 patients received placebo, followed by an open-label treatment period in which participating patients received GENOTROPIN (somatropin [rdna origin]) for up to a total of 24 months. GENOTROPIN (somatropin [rdna origin]) was administered as a daily SC injection at a dose of 0.04 mg/kg/week for the first month of treatment and 0.08 mg/kg/week for subsequent months.
Beneficial changes in body composition were observed at the end of the 6-month treatment period for the patients receiving GENOTROPIN (somatropin [rdna origin]) as compared with the placebo patients. Lean body mass, total body water, and lean/fat ratio increased while total body fat mass and waist circumference decreased. These effects were maintained when this treatment was continued beyond six months period. Bone mineral density declined after 6 months of treatment but returned to baseline values after 12 months of treatment.
Genotropin can be injected using a 2 chamber cartridge that measures the dose perfectly each time, making it very easy to use. Genotropin pens make the HGH injection process a breeze, and they can be performed quickly in the comfort of your own home. There is also a single use vial available for patients needing a specialized dose, or for patients that prefer to simply use a needle and syringe set up.
Genotropin is delivered using a standard insulin needle and is delivered subcutaneously, meaning that it is injected directly underneath the skin, unlike testosterone injections, which are delivered intramuscularly, directly into muscle tissue. The dosage of Gentropin Lyophilized Powder must be adjusted for the individual patient. The weekly dose should be divided into five subcutaneous injections, although some patients may choose to inject twice daily, meaning ten injections. Genotropin injections are delivered five times per week, with two consecutive days off to rest the pituitary and help to preserve its ability to produce human growth hormone independently. GENOTROPIN may be given in the thigh, buttocks, or abdomen; the site of SC injections should be rotated daily to help prevent lipoatrophy.
- Pediatric GHD Patients: Generally, a dose of 0.16 to 0.24 mg/kg body weight/week is recommended.
- Pediatric PWS Patients: Generally, a dose of 0.24 mg/kg body weight/week is recommended.
- Pediatric SGA Patients: Generally, a dose of 0.48 mg/kg body weight/week is recommended.
- Pediatric TS Patients: Generally, a dose of 0.33 mg/kg body weight/week is recommended.Adult GHD Patients: The recommended dosage at the start of therapy is not more than 0.04 mg/kg/week. The dose may be increased at 4 to 8 week periods depending on the individual patient’s requirements to a max. value of 0.08 mg/kg/week, depending upon patient tolerance of the treatment. This approach will tend to result in weight-adjusted doses that are larger for women compared with men and smaller for older and obese patients. Genotropin is highly effective at treating all forms of human growth hormone deficiency. In order to assess the effectiveness of treatment, it is important to measure IGF-1 levels throughout the course of therapy, at least once every six months, in order to make sure that IGF-1 levels remain in the ideal, safe range. IGF-1 is the metabolized form of human growth hormone which leads to most of the benefits of treatment, although human growth hormone does react directly with many receptor sites throughout the body.
Who Makes Genotropin?
Genotropin is manufactured by Pfizer, a global research and pharmaceuticals founded in 1849 by two cousins. The company is publicly traded on the New York Stock Exchange (PFE) and did $67 billion in revenue in 2011.